Joseph Gallo (April 7, 1929 – April 7, 1972), also known as "Crazy Joe", was an Italian-American mobster and Caporegime of the Colombo crime family of New York City.

In his youth, Gallo was diagnosed with schizophrenia after an arrest. He soon became an enforcer in the Profaci crime family, later forming his own crew which included his brothers Larry and Albert. In 1957, Joe Profaci allegedly asked Gallo and his crew to murder Albert Anastasia, the boss of the Gambino crime family; Anastasia was murdered on October 25 at a barber shop in midtown Manhattan. In 1961, the Gallo brothers kidnapped four of Profaci's top men: underboss Joseph Magliocco, Frank Profaci (Joe Profaci's brother), caporegime Salvatore Musacchia and soldato John Scimone, demanding a more favorable financial scheme for the hostages' release. After a few weeks of negotiation, Profaci and his consigliere, Charles "the Sidge" LoCicero, made a deal with the Gallos and secured the peaceful release of the hostages. This incited the First Colombo War.